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An eclectic group of underfunded yet dedicated doctors and nurses navigates caring for patients — and each other — while keeping it all together at an Oregon hospital.
“It's quite the operation.”
2024
Alex is torn between her daughter's school play and an "all-hands" situation in the Emergency Department. Joyce spends the hospital's limited funds on a fancy mammography machine. Matt's first day as a nurse isn't going as he'd hoped.
Joyce's belief that personal life should stay out of the workplace is tested by unexpected news. Ron thinks a patient has a crush on him. Bruce tries to demonstrate the value of his important work.
When Ron hexes the day to prove superstitions aren't real, things at the hospital start getting weird. Joyce and Matt discover an employee's secret.
Alex accidentally provokes the Emergency Department's mean girls. Ron and Serena battle over parking etiquette. Bruce has a hard time letting go of the spotlight.
Ron and Bruce butt heads over a candy bar. Alex is forced to fire an incompetent employee. Matt seeks appreciation for saving a patient's life.
It's the holiday season at St. Denis. Alex and Ron care for a patient whose diagnosis is not what it seems. Joyce enlists Serena's help to boost St. Denis' online presence. Bruce and Matt help a Santa in need.
Ron mocks Alex and Matt's attempts to resolve a conflict between two prison inmates who stabbed each other in a gang fight. Serena helps Bruce address his fear of needles. Joyce finds herself smitten by the burly prison guard.
An "intimacy in the workplace" discussion leads Joyce to discover she's out of the loop on office gossip. Alex gets self-conscious about her sex life. Bruce tries to fight a new policy about dating co-workers.
Joyce asks Alex to be the executor of her estate. Matt and Serena are forced to keep watch over a bickering family. Bruce grapples with unexpected DNA test results.
Ron's bedside manner earns him a complaint from a frustrated patient. Alex insists an unflattering online review was not about her. Bruce confronts his high-school bully.
Joyce pushes the staff to upsell patients on hospital procedures, kicking off some fierce competition and a case of mistaken identity. Bruce and Ron try to play plumber for a day.
An emotional support animal is loose in the halls of St. Denis. Alex goes big for Serena's birthday to mixed results.
When a famous musician's performance at the hospital is delayed, Joyce throws an impromptu talent show with the St. Denis staff. Alex attempts to connect with her daughter, Ella.
Joyce launces a women's health initiative to unexpected results. Ron treats a patient who has all the answers. Bruce has an existential crisis.
Bruce and Alex give conflicting medical advice to a young athlete. Joyce competes with Tiger Woods in her alumni magazine. Matt and Serena (almost) drop an unconscious patient.
Ron's teasing makes Joyce question whether her friendship with a pharmaceutical rep is genuine. Alex has trouble letting Serena take on a new task. Matt finds a mentor in Bruce.
At the annual fundraiser, Alex and her husband, Tim, try to have a wild, kid-free night. Ron and Joyce butt heads over hosting duties. Bruce sets out to win this year's "Dancing with the Caregivers" competition.
A storm causes chaos in the Emergency Department. Alex is torn between an obligation to her husband and her co-workers' needs. Joyce goes on a spending spree with found money.
Wendi McLendon-Covey
Joyce Henderson
Allison Tolman
Alex Mazurkian
Josh Lawson
Bruce Schweitz
Kahyun Kim
Serena Jung
Mekki Leeper
Matt Pearson
Kaliko Kauahi
Val
David Alan Grier
Ron Leonard
2025
Alex tries to hold on to her peaceful vacation vibes. Joyce faces a design crisis in the birthing center. Matt and Serena reassess their working relationship.
After Bruce is attacked at the hospital, Matt helps him deal with the aftermath. Alex motivates Joyce to amp up security, while Ron and Serena debate who is more qualified to defend themselves.
Alex and Ron spar over the wisdom of open communication. Joyce brings in a body scanner that proves overly distracting.
Ron and Bruce butt heads at a medical conference. Joyce tries to show her nurses some love for Nurse Appreciation Week.
Alex is eager to impress her old charge nurse, Pam, who comes back to St. Denis. Serena and Matt try to solve a patient's mystery illness.
Matt struggles to deal with a patient from his past. Bruce tries to rekindle romance with a former flame. Joyce treats patients to cover a nursing shortage.
Ron and Alex react very differently to a seemingly selfless patient. Joyce runs into an old flame. Matt helps Bruce find a new best friend.
With the threat of a nurse walkout, Alex is caught between her colleagues and Joyce. Ron and Bruce go above and beyond to help an unexpected patient.
Ron and Matt try to convince a child to get his shot. Alex helps Joyce with wedding planning. Bruce and Serena butt heads over Matt.
Serena and Alex work a "Botox and Bubbly" party. Joyce enlists Matt's help with a personal issue. Bruce introduces Ron to the world of memecoins.
Alex hosts a senior health fair. Bruce resuscitates a patient with a DNR. Ron competes with Matt over a patient's homemade fudge.
Ron tries to wrap up a perfect visit from his son, Michael. Alex questions Val's return from jury duty. Bruce feels iced out of a juicy business opportunity.
Alex's husband gets treated by Bruce; Joyce goes on an accidental journey; Ron's shoes squeak.
Matt's first birthday party gets crashed by a rival; Joyce decides to "get back out there."
Bruce considers a new chapter in his career; Serena uses a baby to get out of work; Matt helps Ron log onto his computer.
Alex helps Joyce hire a midwife; Bruce joins Matt for an ambulance ride-along; Serena and Ron butt heads over a pen.
Joyce hosts a ribbon-cutting for the birthing center; Matt and Serena take on an awkward assignment.
When Ron becomes a patient, the St. Denis staff rallies around him, whether he likes it or not; Matt and Serena need to talk.
